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How to Travel from Jacksonville to Gainesville

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Traveling from Jacksonville to Gainesville is as simple as a 1-hour and 23-minute ride to the city. Take a bus or pack up your car to arrive at your weekend adventure in no time. And, use our Vacation Guide to discover everything you can do in Gainesville, FL, once you get there. Within, you’ll find the best restaurants, wineries, breweries, shops, events, and more to complete your escape. Everything you need to know about the area is right inside!


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Make Your Trip from Jacksonville to Gainesville

Travel by Bus

Hop on a bus from Jacksonville to Gainesville, FL for a hassle-free journey. While there are a few bus companies you can take to get to your destination, we recommend using Greyhound Bus Company. Not only are they a reliable choice, but they also offer great amenities including free, onboard wifi, charging ports, and reclining seats. Their bus tickets range from $13 to $30 for economy seating depending on the day of the week. Simply purchase your ticket, board, and sit back for the ride.

Travel by Car

The drive from Jacksonville to Gainesville is pretty straightforward. Follow Interstate 10 until you reach Highway 301 South. This will lead you directly into the heart of Gainesville, FL!

Yes, it’s really that easy.

If you’re looking for ways to pass the time during your travels, a car ride is the best time to catch of with someone you haven’t heard from in a while. Talking to someone will make the already short drive go by even faster! Or, consider playing the “license plate game,” where you keep track of how many different states you can spot on cars’ tags.

What to Do in Gainesville

There are so many things to do in Gainesville, FL. Enjoy our fantastic nightlife at the iconic arcade bar or swanky dueling piano bar. Or, during the day, stop in for a sporting event at the University of Florida, take a dip in natural springs like Devil’s Den, or paddle down the Santa Fe River.

Stay the Weekend at Sweetwater Branch InnWine and Cheese Hour

Now that you’re ready to start your journey from Jacksonville to Gainesville, it’s important that you have a place to stay. Sweetwater Branch Inn is the perfect destination for your weekend exploring the city! We’re located only blocks away from the heart of downtown Gainesville, and also offer plenty of onsite amenities to make your stay as comfortable as possible including a pool, mini-golf, and a complimentary Wine & Cheese Hour.

There are plenty of accommodations at our Victorian-style inn. We suggest staying in one of our first floor rooms, like the Piccadilly Suite, so you’re only a few steps away from stepping onto the city streets. This room also comes with a separate sunroom with a cozy couch, along with a plush, queen-size bed. Reserve your stay with us to complete your trip!

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